Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184864 | 0.90 | AR (0.64) | ARHDAC1NR3C1 | |
| SCHEMBL1715562 | 0.90 | AR (0.64) | ARHDAC1NR3C1 | |
| SCHEMBL20003468 | 0.88 | AR (0.60) | ARHDAC1NR3C1 | |
| SCHEMBL20003450 | 0.84 | AR (0.55) | ARHDAC1NR3C1 | |
| SCHEMBL2632993 | 0.83 | AR (0.57) | ARHDAC1NR3C1 | |
| SCHEMBL7034839 | 0.83 | AR (0.57) | ARHDAC1NR3C1 | |
| SCHEMBL20003460 | 0.83 | AR (0.58) | ARNR3C1 | |
| SCHEMBL7031925 | 0.82 | AR (0.66) | AR | |
| SCHEMBL20003471 | 0.81 | AR (0.56) | ARNR3C1 | |
| SCHEMBL21155267 | 0.80 | AR (0.56) | ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086718-A1 | Diarylhydantoin Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086718-A1 | Diarylhydantoin Compounds | BPHL, AR, SHBG | AR 2/4885HDAC1 183/4885NR3C1 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.