Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739489 | 1.00 | DPP7 (0.36) | DPP7DPP4DPP9RRM1METAP1 | |
| SCHEMBL1274426 | 0.82 | CA12 (0.35) | DPP7DPP4DPP9RRM1METAP1 | |
| SCHEMBL2189880 | 0.82 | CA12 (0.35) | DPP7DPP4DPP9RRM1METAP1 | |
| SCHEMBL2739680 | 0.82 | ALDH1A1 (0.48) | DPP7DPP4DPP9BLMKMT2A | |
| SCHEMBL2739537 | 0.82 | ALDH1A1 (0.48) | DPP7DPP4DPP9BLMKMT2A | |
| SCHEMBL2739441 | 0.82 | ALDH1A1 (0.48) | DPP7DPP4DPP9BLMKMT2A | |
| SCHEMBL20807626 | 0.80 | PTGS1 (0.44) | DPP7METAP1ALOX15BLMPMP22 | |
| SCHEMBL21153856 | 0.80 | PTGS1 (0.44) | DPP7METAP1ALOX15BLMPMP22 | |
| SCHEMBL24709575 | 0.78 | SLC22A6 (0.37) | ALOX15BLMPMP22KMT2AALDH1A1 | |
| SCHEMBL7541728 | 0.78 | BLM (0.54) | DPP7DPP4DPP9RRM1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444411-A1 | TRIPEPTIDE BORONIC ACID OR BORONIC ESTER, PREPARATIVE METHOD AND USE THEREOF | Peking University (CN) | 2012-04-25 | — | — | EP | disclosed |