SCHEMBL26331966

SCHEMBL26331966

CCOCCOCCCNC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
TSHR P16473 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 1/20 0.45
MGLL Q99685 1/20 0.45
HPGD P15428 2/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
POLB P06746 2/20 0.42
PKM P14618 1/20 0.41
USP2 O75604 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18758187 0.97 SMN1; SMN2 (0.53) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL12284024 0.93 MGLL (0.51) SMN1; SMN2TSHRHSD17B10RAB9AALDH1A1
SCHEMBL17486903 0.93 MGLL (0.51) SMN1; SMN2TSHRHSD17B10RAB9AALDH1A1
SCHEMBL13401575 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL15143431 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL24136290 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL16329201 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL24591874 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL16546771 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7
SCHEMBL13311294 0.92 MGLL (0.47) SMN1; SMN2TSHRHSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11717577-B2 Method for preparing long-acting drug conjugate through preparation of intermediate HANMI PHARM. CO., LTD. (KR) 2023-08-08 US disclosed
US-11717577-B2 Method for preparing long-acting drug conjugate through preparation of intermediate HANMI PHARM. CO., LTD. (KR) 2023-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11717577-B2 Method for preparing long-acting drug conjugate through preparation of intermediate GNRHR, UGT1A7, UGT1A3 SMN1; SMN2 541/4885TSHR 406/4885HSD17B10 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.