Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 10/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 7/20 | 0.52 |
| ▸ | DNMT3L | Q9UJW3 | 5/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26314528 | 0.91 | USP2 (0.55) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24003837 | 0.89 | MAPT (0.54) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24003754 | 0.87 | USP2 (0.51) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL26332088 | 0.86 | DNMT1 (0.52) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL26314582 | 0.85 | USP2 (0.54) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL26331749 | 0.85 | DNMT1 (0.52) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL26331722 | 0.84 | DNMT1 (0.69) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23999381 | 0.83 | USP2 (0.59) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24006111 | 0.82 | DNMT1 (0.66) | USP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24003982 | 0.82 | DNMT1 (0.66) | USP2MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | USP2 3789/4885MAPT 3962/4885KMT2A 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.