SCHEMBL2633271

SCHEMBL2633271

c1ccc2oc(-c3ccc4ccc(-c5nc6ccccc6o5)cc4c3)nc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.64
RAB9A P51151 9/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
ATM Q13315 1/20 0.64
ALDH1A1 P00352 10/20 0.59
HPGD P15428 9/20 0.59
KDM4E B2RXH2 8/20 0.59
SMN1; SMN2 Q16637 7/20 0.59
TP53 P04637 5/20 0.59
HSD17B10 Q99714 6/20 0.58
MAPT P10636 5/20 0.57
HCRTR1 O43613 3/20 0.57
NFKB1 P19838 2/20 0.57
STAT1 P42224 2/20 0.57
NFKB2 Q00653 2/20 0.57
RELA Q04206 2/20 0.57
GAA P10253 2/20 0.57
LMNA P02545 1/20 0.57
GFER P55789 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1913541 0.95 NPC1 (0.62) NPC1RAB9AMEN1KMT2AATM
SCHEMBL30727501 0.95 NPC1 (0.62) NPC1RAB9AMEN1KMT2AATM
SCHEMBL2174585 0.94 NPC1 (0.66) NPC1RAB9AMEN1KMT2AATM
SCHEMBL2220920 0.93 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL19310468 0.93 NPC1 (0.65) NPC1RAB9AMEN1KMT2AATM
SCHEMBL19846117 0.93 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL19846146 0.93 NPC1 (0.64) NPC1RAB9AMEN1KMT2AATM
SCHEMBL17691814 0.89 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL19846119 0.88 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM
SCHEMBL31170 0.86 NPC1 (0.81) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9557670-B2 Toner, developer, and color toner set RICOH COMPANY, LTD. (JP) 2017-01-31 US disclosed
US-9557670-B2 Toner, developer, and color toner set RICOH COMPANY, LTD. (JP) 2017-01-31 US disclosed
US-20150024312-A1 TONER, DEVELOPER, AND COLOR TONER SET RICOH COMPANY, LTD. (JP) 2015-01-22 US disclosed
US-20150024312-A1 TONER, DEVELOPER, AND COLOR TONER SET RICOH COMPANY, LTD. (JP) 2015-01-22 US disclosed
EP-1983378-B1 Magenta toner for developing electrostatic image KONICA MINOLTA BUSINESS TECH (JP) 2012-04-25 EP disclosed
US-8062819-B2 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-11-22 US disclosed
US-8062819-B2 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-11-22 US disclosed
US-20080261141-A1 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-10-23 US disclosed
US-20080261141-A1 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-10-23 US disclosed
EP-1983378-A2 Magenta toner for developing electrostatic image KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-10-22 EP disclosed