⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537023 | 0.86 | — | — | |
| SCHEMBL11050561 | 0.85 | — | — | |
| SCHEMBL263579 | 0.80 | — | — | |
| SCHEMBL3233349 | 0.74 | — | — | |
| SCHEMBL167234 | 0.74 | — | — | |
| SCHEMBL10402979 | 0.74 | — | — | |
| SCHEMBL551633 | 0.66 | ALDH1A1 (0.34) | — | |
| SCHEMBL2044104 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL4043116 | 0.64 | — | — | |
| SCHEMBL822919 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967197-B2 | Thiazepinyl hydroxamic acid derivatives as matrix metalloproteinase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-22 | — | — | US | claimed |
| US-6660858-B2 | Made by reacting a benzoxazole with a leaving group at the 2 position and a diamine of given formula | LION BIOSCIENCE AG (DE) | 2003-12-09 | — | — | US | claimed |
| US-20030134849-A1 | Thiazepinyl hydroxamic acid derivatives as matrix metalloproteinase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | US | claimed |
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |
| EP-1259499-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | claimed |
| US-20020161028-A1 | 2-aminobenzoxazole derivatives and combinatorial libraries thereof | LION BIOSCIENCE, AG (DE) | 2002-10-31 | — | — | US | claimed |
| WO-2002079753-A2 | 2-AMINOBENZOXAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-10-10 | — | — | WO | claimed |
| WO-2001060808-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | claimed |
| US-4402981-A | ANTIULCER AGENT | KALI-CHEMIE PHARMA, GMBH (DE) | 1983-09-06 | — | — | US | claimed |
| US-20190071407-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2019-03-07 | — | — | US | disclosed |
| US-10155730-B2 | Isoxazoline derivatives as insecticides | SYNGENTA CROP PROTECTION, LLC (US) | 2018-12-18 | — | — | US | disclosed |
| US-9558863-B2 | Electrically conductive polymers with enhanced conductivity | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2017-01-31 | — | — | US | disclosed |
| US-20160368883-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2016-12-22 | — | — | US | disclosed |
| US-9243111-B2 | Water-soluble electrically conductive polymers | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2016-01-26 | — | — | US | disclosed |
| EP-0004529-A2 | Tantomeric arylaminoimidazoline derivatives, their preparation and pharmaceutical formulations for analgetic application containing them | Lentia Gesellschaft mit beschränkter Haftung (DE) | 1979-10-17 | — | — | EP | disclosed |
| US-4149000-A | ANTAGONISTS OF NARCOTIC ANALGESICS | STERLING DRUG INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4142051-A | Arylaminoimidazoline derivatives | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1979-02-27 | — | — | US | disclosed |
| US-4093812-A | MICROBIOCIDES, DISINFECTANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4009171-A | ANTAGONISTS OF NARCOTIC ANALGESICS | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |