Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 6/20 | 0.61 |
| ▸ | TACR2 | P21452 | 5/20 | 0.61 |
| ▸ | TACR1 | P25103 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24855510 | 0.84 | POLB (0.46) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| SCHEMBL26336625 | 0.84 | TACR2 (0.53) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| SCHEMBL7750574 | 0.78 | TACR2 (0.83) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| SCHEMBL24855499 | 0.77 | CCR5 (0.54) | L3MBTL1ALDH1A1KMT2ALMNADRD2 | |
| Osanetant SCHEMBL29371450 | 0.76 | TACR2 (1.00) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| Osanetant SCHEMBL119440 | 0.76 | TACR2 (1.00) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| Osanetant SCHEMBL30961738 | 0.76 | TACR2 (1.00) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| Osanetant SCHEMBL5679271 | 0.76 | TACR2 (1.00) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| Osanetant SCHEMBL4080131 | 0.76 | TACR2 (1.00) | TACR3TACR2TACR1CYP3A4CYP2D6 | |
| Osanetant SCHEMBL6543149 | 0.75 | TACR2 (0.98) | TACR3TACR2TACR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271015-B1 | NK-3 RECEPTOR ANTAGONISTS FOR THERAPEUTIC OR COSMETIC TREATMENT OF EXCESS BODY FAT | OGEDA S A (BE) | 2023-09-27 | — | — | EP | disclosed |