SCHEMBL26337188

SCHEMBL26337188

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nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25949255 0.87 LMNA (0.37)
SCHEMBL14895459 0.74 HSD17B10 (0.39) HSD17B10TDP1USP2
SCHEMBL8524164 0.73 TDP1 (0.33) TDP1
SCHEMBL27953891 0.70 USP2 (0.50) HSD17B10TDP1USP2
SCHEMBL23220483 0.68 TDP1 (0.36) TDP1
SCHEMBL14618765 0.68 TDP1 (0.36) TDP1
SCHEMBL14747616 0.68 TDP1 (0.36) TDP1
SCHEMBL23220490 0.68 TDP1 (0.36) TDP1
SCHEMBL21782825 0.68 TDP1 (0.36) TDP1
SCHEMBL18332860 0.68 LMNA (0.34) TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230302041-A1 Competitive Self-Blocking with Unlabeled Manocept Imaging Agents SCOTT, JOHN KIM, JR. 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302041-A1 Competitive Self-Blocking with Unlabeled Manocept Imaging Agents MANBA, MAN2B2, MAN2B1 HSD17B10 3941/4885TDP1 4838/4885USP2 3166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.