Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633837 | 0.95 | HRH3 (0.39) | HRH3 | |
| Hydrochloric Acid SCHEMBL2637048 | 0.94 | HRH3 (0.38) | HRH3 | |
| SCHEMBL2633886 | 0.93 | HRH3 (0.33) | HRH3 | |
| SCHEMBL2633784 | 0.92 | HRH3 (0.35) | HRH3 | |
| SCHEMBL2633862 | 0.92 | HRH3 (0.35) | HRH3 | |
| SCHEMBL2633787 | 0.92 | HRH3 (0.36) | HRH3 | |
| Hydrochloric Acid SCHEMBL2633808 | 0.91 | HRH3 (0.36) | HRH3 | |
| SCHEMBL2633779 | 0.90 | HRH3 (0.31) | HRH3 | |
| SCHEMBL2633858 | 0.87 | HRH3 (0.43) | HRH3 | |
| SCHEMBL2633796 | 0.87 | HRH3 (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569304-A1 | SUBSTITUTED N-HETEROARYL SPIROLACTAM BIPYRROLIDINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-03-20 | — | — | EP | claimed |
| WO-2011143148-A1 | SUBSTITUTED N-HETEROARYL SPIROLACTAM BIPYRROLIDINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-11-17 | — | — | WO | claimed |
| EP-2569304-A1 | SUBSTITUTED N-HETEROARYL SPIROLACTAM BIPYRROLIDINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011143148-A1 | SUBSTITUTED N-HETEROARYL SPIROLACTAM BIPYRROLIDINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-11-17 | — | — | WO | disclosed |