Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19895429 | 1.00 | TSHR (0.58) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL5084469 | 0.98 | TSHR (0.62) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL19895416 | 0.98 | TSHR (0.62) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL19895420 | 0.98 | TSHR (0.62) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL19895425 | 0.98 | TSHR (0.62) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL19895419 | 0.98 | TSHR (0.62) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL14481041 | 0.93 | TSHR (0.68) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL19895403 | 0.93 | TSHR (0.59) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL7853536 | 0.93 | TSHR (0.68) | TSHRTRPV1PPARGFFAR1PPARD | |
| SCHEMBL25186111 | 0.93 | TSHR (0.67) | TSHRTRPV1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001858-B | Compounds comprising modified diorganosiloxane polymers | 3M创新有限公司 | 2020-05-15 | — | — | CN | disclosed |
| US-10487180-B2 | Compounds comprising modified diorganosiloxane polymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-11-26 | — | — | US | disclosed |
| US-10457700-B2 | Platinum prodrugs and methods of making and using thereof | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-20180044362-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2018-02-15 | — | — | US | disclosed |
| US-20170362391-A1 | COMPOUNDS COMPRISING MODIFIED DIORGANOSILOXANE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-12-21 | — | — | US | disclosed |
| US-9480751-B2 | Albumin binding probes and drug conjugates thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-11-01 | — | — | US | disclosed |
| WO-2016144889-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016094199-A1 | COMPOUNDS COMPRISING MODIFIED DIORGANOSILOXANE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-06-16 | — | — | WO | disclosed |
| EP-2437786-B1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RES & DEV (IL) | 2016-05-18 | — | — | EP | disclosed |
| US-20150202310-A1 | ALBUMIN BINDING PROBES AND DRUG CONJUGATES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) | 2015-07-23 | — | — | US | disclosed |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-04-02 | — | — | US | disclosed |
| EP-2696897-A2 | ALBUMIN BINDING PROBES AND DRUG CONJUGATES THEREOF | Yeda Research and Development Co. Ltd. (IL) | 2014-02-19 | — | — | EP | disclosed |
| WO-2012140647-A2 | ALBUMIN BINDING PROBES AND DRUG CONJUGATES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) | 2012-10-18 | — | — | WO | disclosed |
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-05-31 | — | — | US | disclosed |
| EP-2437786-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | Yeda Research and Development Co. Ltd. (IL) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010140148-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | YEDA RESEARCH AND DEVELOPMENT CO . LTD (IL) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457700-B2 | Platinum prodrugs and methods of making and using thereof | MGMT, DPYD, OGG1 | TSHR 4229/4885TRPV1 4160/4885PPARG 2265/4885 |
| US-20150202310-A1 | ALBUMIN BINDING PROBES AND DRUG CONJUGATES THEREOF | FABP1, FABP5, ALB | TSHR 2860/4885TRPV1 3679/4885PPARG 355/4885 |
| US-20180044362-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | MGMT, DPYD, OGG1 | TSHR 4229/4885TRPV1 4160/4885PPARG 2265/4885 |
| US-20120134977-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | ALB, DNPEP, CNDP2 | TSHR 2803/4885TRPV1 2814/4885PPARG 1439/4885 |
| US-20150093370-A1 | PRODRUGS CONTAINING ALBUMIN BINDING PROBE | ALB, DNPEP, CNDP2 | TSHR 2803/4885TRPV1 2814/4885PPARG 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.