Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.45 |
| ▸ | PDE9A | O76083 | 8/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26345453 | 0.99 | PDE2A (0.43) | PDE2APDE9AP2RX3ALDH1A1MAPT | |
| SCHEMBL26345338 | 0.95 | PDE9A (0.40) | PDE2APDE9AP2RX3LMNAHPGD | |
| SCHEMBL26983383 | 0.89 | P2RX3 (0.37) | PDE2AP2RX3ALDH1A1LMNA | |
| SCHEMBL26344125 | 0.83 | PDE9A (0.45) | PDE2APDE9AP2RX3LMNA | |
| SCHEMBL30459333 | 0.79 | CYP3A4 (0.39) | PDE2APDE9AP2RX3ALDH1A1MAPT | |
| SCHEMBL26344132 | 0.79 | CYP3A4 (0.39) | PDE2APDE9AP2RX3ALDH1A1MAPT | |
| SCHEMBL31363880 | 0.79 | PARP1 (0.40) | PDE2APDE9AP2RX3ALDH1A1MAPT | |
| SCHEMBL31364035 | 0.79 | CYP3A4 (0.39) | PDE2APDE9AP2RX3ALDH1A1MAPT | |
| SCHEMBL26344141 | 0.79 | PARP1 (0.40) | PDE2APDE9AP2RX3ALDH1A1MAPT | |
| SCHEMBL29588283 | 0.74 | CYP3A4 (0.40) | PDE2APDE9AP2RX3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |