Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867068 | 0.84 | ESR2 (0.46) | RYR2 | |
| SCHEMBL12265293 | 0.83 | RYR2 (0.45) | RYR2NOTUM | |
| SCHEMBL12265295 | 0.83 | RYR2 (0.42) | RYR2NOTUM | |
| SCHEMBL8196121 | 0.82 | RYR2 (0.39) | RYR2 | |
| SCHEMBL12265292 | 0.79 | RYR2 (0.39) | RYR2 | |
| SCHEMBL12265289 | 0.77 | RYR2 (0.53) | RYR2 | |
| SCHEMBL10074436 | 0.74 | ESR2 (0.45) | RYR2 | |
| SCHEMBL26344276 | 0.74 | RYR2 (0.53) | RYR2 | |
| SCHEMBL29984129 | 0.73 | RYR2 (0.48) | RYR2NOTUM | |
| SCHEMBL27080007 | 0.73 | RYR2 (0.48) | RYR2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302013-A1 | METHOD OF TREATING VIRAL-INDUCED COGNITIVE DYSFUNCTION BY TARGETING LEAKY RyR2 CHANNELS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302013-A1 | METHOD OF TREATING VIRAL-INDUCED COGNITIVE DYSFUNCTION BY TARGETING LEAKY RyR2 CHANNELS | RYR2, RYR1, CACNB1 | RYR2 1/4885NOTUM 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.