Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867303 | 0.90 | RYR2 (0.72) | RYR2KCNH2 | |
| SCHEMBL26942271 | 0.87 | RYR2 (0.73) | RYR2KCNH2 | |
| SCHEMBL6867153 | 0.85 | RYR2 (0.54) | RYR2KCNH2 | |
| SCHEMBL26344276 | 0.83 | RYR2 (0.53) | RYR2 | |
| SCHEMBL6866946 | 0.82 | RYR2 (0.72) | RYR2 | |
| SCHEMBL26344322 | 0.80 | RYR2 (0.58) | RYR2 | |
| SCHEMBL6866678 | 0.79 | RYR2 (0.57) | RYR2 | |
| SCHEMBL13392530 | 0.79 | RYR2 (0.49) | RYR2 | |
| SCHEMBL17946170 | 0.78 | RYR2 (0.65) | RYR2 | |
| SCHEMBL13392524 | 0.78 | RYR2 (0.72) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302013-A1 | METHOD OF TREATING VIRAL-INDUCED COGNITIVE DYSFUNCTION BY TARGETING LEAKY RyR2 CHANNELS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302013-A1 | METHOD OF TREATING VIRAL-INDUCED COGNITIVE DYSFUNCTION BY TARGETING LEAKY RyR2 CHANNELS | RYR2, RYR1, CACNB1 | RYR2 1/4885KCNH2 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.