Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634175 | 0.83 | PDE10A (0.74) | PDE10A | |
| SCHEMBL7695813 | 0.83 | PDE10A (0.63) | PDE10A | |
| SCHEMBL7693747 | 0.83 | PDE10A (0.63) | PDE10A | |
| Hydrochloric Acid SCHEMBL2634059 | 0.82 | PDE10A (0.61) | PDE10A | |
| SCHEMBL2634139 | 0.81 | PDE10A (0.66) | PDE10A | |
| SCHEMBL2637288 | 0.80 | PDE10A (0.62) | PDE10A | |
| SCHEMBL7697024 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7706158 | 0.77 | PDE10A (0.62) | PDE10A | |
| SCHEMBL7706102 | 0.77 | PDE10A (0.65) | PDE10A | |
| SCHEMBL15134894 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569306-A1 | HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS | Amgen Inc. (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011143366-A1 | HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |