Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317330 | 0.82 | MAPK1 (0.62) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL26332927 | 0.80 | MAPK1 (0.61) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL34468119 | 0.80 | TSHR (0.66) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL13753343 | 0.77 | TSHR (0.72) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL13753401 | 0.77 | HPGD (0.71) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL28474528 | 0.76 | MAPK1 (0.55) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL8586880 | 0.76 | MAPK1 (0.56) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL18118621 | 0.74 | RAB9A (0.69) | MAPK1TSHRESR2POLBKMT2A | |
| Fenfuram SCHEMBL18978 | 0.74 | SMN1; SMN2 (0.73) | MAPK1ESR2POLBKMT2AMEN1 | |
| SCHEMBL13753464 | 0.74 | HPGD (0.71) | MAPK1TSHRESR2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |