Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 4/20 | 0.40 |
| ▸ | AOC2 | O75106 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26284042 | 1.00 | PTGDR (0.40) | PTGDRAOC2MAOAKDM4EALDH1A1 | |
| SCHEMBL26284074 | 0.92 | PTGDR (0.42) | PTGDRAOC2MAOAKDM4EALDH1A1 | |
| SCHEMBL26284110 | 0.91 | PTGDR (0.40) | PTGDRAOC2MAOAKDM4EALDH1A1 | |
| SCHEMBL24025489 | 0.90 | AOC2 (0.49) | AOC2MAOAMAOB | |
| SCHEMBL24058351 | 0.90 | AOC2 (0.49) | AOC2MAOAMAOB | |
| SCHEMBL24025663 | 0.87 | F13A1 (0.40) | PTGDRAOC2MAOAKDM4EALDH1A1 | |
| SCHEMBL26345753 | 0.87 | MAOB (0.41) | PTGDRAOC2KDM4EALDH1A1MAOB | |
| SCHEMBL26345713 | 0.87 | MAOB (0.37) | PTGDRAOC2MAOAKDM4EALDH1A1 | |
| SCHEMBL26283924 | 0.86 | KDM4E (0.46) | PTGDRKDM4EALDH1A1TSHRATM | |
| SCHEMBL26345567 | 0.84 | AOC2 (0.40) | PTGDRAOC2MAOAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873599-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-27 | — | — | EP | disclosed |