SCHEMBL26346901

SCHEMBL26346901

CCC(=O)NCCC(C)(C)OCCC(C)(C)OCCN

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18900096 0.88 MEN1 (0.44) MEN1KMT2ARECQL
SCHEMBL24262515 0.86 MEN1 (0.41) MEN1KMT2ARECQL
SCHEMBL24489203 0.85 MEN1 (0.44) MEN1KMT2ARECQL
SCHEMBL22923613 0.84 MEN1 (0.40) MEN1KMT2ARECQL
SCHEMBL18133883 0.84 PAOX (0.42)
SCHEMBL23919438 0.83 MEN1 (0.45) MEN1KMT2ARECQL
SCHEMBL20648082 0.82 MEN1 (0.38) MEN1KMT2ARECQL
SCHEMBL24376196 0.80 MEN1 (0.45) MEN1KMT2A
SCHEMBL25896444 0.80 MEN1 (0.48) MEN1KMT2ARECQL
SCHEMBL24489332 0.79 MEN1 (0.41) MEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303649-A1 MODIFIED IL-2 POLYPEPTIDES FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES BRIGHT PEAK THERAPEUTICS AG (CH) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303649-A1 MODIFIED IL-2 POLYPEPTIDES FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES IL2, IL2RA, ICOS MEN1 4197/4885KMT2A 1964/4885RECQL 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.