Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489203 | 0.88 | MEN1 (0.44) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| SCHEMBL25896444 | 0.85 | MEN1 (0.48) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| SCHEMBL24489332 | 0.85 | MEN1 (0.41) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| SCHEMBL24262515 | 0.85 | MEN1 (0.41) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| SCHEMBL26346901 | 0.83 | MEN1 (0.40) | MEN1KMT2ARECQL | |
| SCHEMBL18900096 | 0.83 | MEN1 (0.44) | MEN1KMT2ARECQL | |
| SCHEMBL22923613 | 0.83 | MEN1 (0.40) | MEN1KMT2ARECQL | |
| SCHEMBL20144557 | 0.83 | SMN1; SMN2 (0.40) | KMT2A | |
| SCHEMBL13629818 | 0.82 | CASP2 (0.47) | — | |
| SCHEMBL22788592 | 0.81 | MEN1 (0.42) | MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892272-A1 | BIFUNCTIONAL MOLECULES FOR DEGRADATION OF EGFR AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |