SCHEMBL263472

SCHEMBL263472

CC(=Cc1c(F)c(F)c(F)c(F)c1F)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.45
APEX1 P27695 10/20 0.41
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TBXAS1 P24557 3/20 0.32
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466254 1.00 AKR1C3 (0.45) AKR1C3APEX1MEN1KMT2ATBXAS1
SCHEMBL4309359 0.87 AKR1C3 (0.39) AKR1C3APEX1
SCHEMBL7138000 0.83 AKR1C3 (0.44) AKR1C3APEX1
SCHEMBL7137993 0.83 AKR1C3 (0.44) AKR1C3APEX1
SCHEMBL10853566 0.77 CYP1A2 (0.35) MEN1KMT2A
SCHEMBL10853570 0.77 CYP1A2 (0.35) MEN1KMT2A
SCHEMBL7130597 0.77 AKR1C3 (0.47) AKR1C3APEX1
SCHEMBL19946327 0.77 AKR1C3 (0.42) AKR1C3APEX1TBXAS1
SCHEMBL7130604 0.77 AKR1C3 (0.47) AKR1C3APEX1
SCHEMBL19946328 0.77 AKR1C3 (0.42) AKR1C3APEX1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850018-B1 ANTIMICROBIAL CONTACT LENSES KERAMED INC (US) 2023-08-23 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-3031947-B1 POLYMER THIN FILM WITH WATER REPELLENCY AND OIL REPELLENCY, AND METHOD FOR PREPARING SAME LG CHEMICAL LTD (KR) 2021-02-24 EP claimed
EP-3077429-B1 SOFT HYDROPHOBIC ACRYLIC MATERIALS NOVARTIS AG (CH) 2018-09-26 EP claimed
EP-2443486-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-03-01 EP claimed
EP-2401309-B1 ELECTRICALLY ISOLATING POLYMER COMPOSITION CORNING INC (US) 2015-06-17 EP claimed
US-20150148903-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2015-05-28 US claimed
US-8133960-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US claimed
EP-1498978-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME UBE INDUSTRIES (JP) 2010-09-08 EP claimed
US-20090250588-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2009-10-08 US claimed
EP-1583568-B1 PROCESS FOR THE PREPARATION OF BIOMEDICAL DEVICES WITH PEPTIDE CONTAINING COATINGS JOHNSON & JOHNSON VISION CARE (US) 2009-01-21 EP claimed
EP-1026525-B1 Graded index optical fibre MITSUBISHI RAYON CO (JP) 2007-10-10 EP claimed
US-6341190-B1 Organic optical components and preparation thereof EPIGEM LIMITED (GB) 2002-01-22 US claimed
EP-0722387-B1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LIMITED (GB) 2000-09-06 EP claimed
US-5985084-A Organic optical components and preparation thereof EPIGEM LTD. (GB) 1999-11-16 US claimed
EP-0722387-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF Epigem Limited (GB) 1996-07-24 EP claimed
US-5496675-A Carrier coating and processes XEROX CORPORATION (US) 1996-03-05 US claimed
WO-1995009726-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LTD (GB) 1995-04-13 WO claimed
WO-2024009732-A1 POSITIVE-ACTING PHOTOSENSITIVE RESIN COMPOSITION 日本ポリテック株式会社 2024-01-11 WO disclosed
EP-0267459-A1 Transparent polymers HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-18 EP disclosed