SCHEMBL4309359

SCHEMBL4309359

CC(=Cc1c(F)c(F)c(F)c2c(F)c(F)c(F)c(F)c12)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.39
APEX1 P27695 9/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263472 0.87 AKR1C3 (0.45) AKR1C3APEX1
SCHEMBL466254 0.87 AKR1C3 (0.45) AKR1C3APEX1
SCHEMBL7137993 0.72 AKR1C3 (0.44) AKR1C3APEX1
SCHEMBL7138000 0.72 AKR1C3 (0.44) AKR1C3APEX1
SCHEMBL19946327 0.71 AKR1C3 (0.42) AKR1C3APEX1
SCHEMBL19946328 0.71 AKR1C3 (0.42) AKR1C3APEX1
SCHEMBL7130597 0.71 AKR1C3 (0.47) AKR1C3APEX1
SCHEMBL7130604 0.71 AKR1C3 (0.47) AKR1C3APEX1
SCHEMBL124742 0.69 AKR1C3 (0.48) AKR1C3APEX1
SCHEMBL124743 0.69 AKR1C3 (0.48) AKR1C3APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090264610-A1 Novel Copolymer of Methacrylic Ester, Composition, Optical Element and Electric Member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-10-22 US claimed
CN-101432325-A Novel copolymer of methacrylic ester, composition, optical element and electric member JAPAN SCIENCE & TECH AGENCY (JP) 2009-05-13 CN claimed
WO-2007129418-A1 NOVEL COPOLYMER OF METHACRYLIC ESTER, COMPOSITION, OPTICAL ELEMENT AND ELECTRIC MEMBER JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-11-15 WO claimed
US-8435610-B2 Copolymer of (meth)acrylic ester, composition, optical element and electric member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-05-07 US disclosed
US-20090264610-A1 Novel Copolymer of Methacrylic Ester, Composition, Optical Element and Electric Member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-10-22 US disclosed
CN-101432325-A Novel copolymer of methacrylic ester, composition, optical element and electric member JAPAN SCIENCE & TECH AGENCY (JP) 2009-05-13 CN disclosed
WO-2007129418-A1 NOVEL COPOLYMER OF METHACRYLIC ESTER, COMPOSITION, OPTICAL ELEMENT AND ELECTRIC MEMBER JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-11-15 WO disclosed