Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849385 | 0.83 | PIK3CG (0.37) | PIK3CGCCNE2CCNE1CDK2PIK3CA | |
| SCHEMBL21325313 | 0.82 | NUDT1 (0.35) | PIK3CGCCNE2CCNE1CDK2 | |
| SCHEMBL21533814 | 0.79 | TLR7 (0.33) | PIK3CGCCNE2CCNE1CDK2 | |
| SCHEMBL13561302 | 0.79 | CCNE2 (0.34) | PIK3CGCCNE2CCNE1CDK2 | |
| SCHEMBL18167004 | 0.78 | CCNE2 (0.36) | PIK3CGCCNE2CCNE1CDK2PIK3CA | |
| SCHEMBL18167003 | 0.78 | PIK3CG (0.36) | PIK3CGCCNE2CCNE1CDK2PIK3CA | |
| SCHEMBL19179773 | 0.78 | PIK3CG (0.39) | PIK3CGCCNE2CCNE1CDK2PIK3CA | |
| SCHEMBL17109715 | 0.78 | PIK3CG (0.36) | PIK3CGCCNE2CCNE1CDK2PIK3CA | |
| SCHEMBL13561299 | 0.78 | PIK3CG (0.36) | PIK3CGCCNE2CCNE1CDK2PIK3CA | |
| SCHEMBL23052753 | 0.77 | PIK3CG (0.31) | PIK3CGCCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303566-A1 | INHIBITORS OF RAF KINASES | Pierre Fabre Médicament (FR) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303566-A1 | INHIBITORS OF RAF KINASES | BRAF, RAF1, ARAF | PIK3CG 156/4885TLR8 3021/4885CCNE2 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.