Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 16/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26347502 | 0.85 | CHRM5 (1.00) | CHRM5CHRM1 | |
| SCHEMBL30410553 | 0.85 | CHRM5 (1.00) | CHRM5CHRM1 | |
| SCHEMBL26347729 | 0.85 | CHRM5 (1.00) | CHRM5CHRM1ALDH1A1POLBLMNA | |
| SCHEMBL28983104 | 0.84 | CHRM5 (0.73) | CHRM5ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL28983120 | 0.84 | CHRM5 (0.73) | CHRM5CHRM1ALDH1A1POLBLMNA | |
| SCHEMBL30410256 | 0.84 | CHRM5 (0.73) | CHRM5CHRM1ALDH1A1POLBLMNA | |
| SCHEMBL28983152 | 0.84 | CHRM5 (0.72) | CHRM5ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL28983165 | 0.83 | CHRM5 (0.71) | CHRM5CHRM1ALDH1A1LMNAMEN1 | |
| SCHEMBL28983186 | 0.83 | CHRM5 (0.71) | CHRM5ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL28983188 | 0.83 | CHRM5 (0.71) | CHRM5ALDH1A1POLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | claimed |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | VANDERBILT UNIVERSITY | 2023-09-28 | — | — | US | disclosed |
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | CHRM5, CHRM1, CHRM2 | CHRM5 1/4885CHRM1 2/4885ALDH1A1 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.