Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 10/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983104 | 0.93 | CHRM5 (0.73) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983119 | 0.92 | CHRM5 (0.69) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983188 | 0.92 | CHRM5 (0.71) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983186 | 0.92 | CHRM5 (0.71) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983184 | 0.90 | CHRM5 (0.69) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983165 | 0.90 | CHRM5 (0.71) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983167 | 0.87 | CHRM5 (0.62) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL26347488 | 0.84 | CHRM5 (1.00) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983123 | 0.83 | ALDH1A1 (0.86) | CHRM5ALDH1A1LMNAALOX15MAPK1 | |
| SCHEMBL28983145 | 0.83 | CHRM5 (0.73) | CHRM5ALDH1A1LMNAALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | claimed |
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | disclosed |