SCHEMBL26348017

SCHEMBL26348017

Cc1ccc2c(c1)N(C(=O)NC(C)C)CC(=O)C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
AADAT Q8N5Z0 1/20 0.35
P2RX4 Q99571 1/20 0.34
DPP8 Q6V1X1 2/20 0.34
DPP9 Q86TI2 2/20 0.34
DPP7 Q9UHL4 1/20 0.34
RAB9A P51151 4/20 0.33
NPC1 O15118 3/20 0.33
MAPT P10636 1/20 0.33
BCHE P06276 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NAMPT P43490 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PDE5A O76074 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25464478 0.80 NPC1 (0.49) NOTUMKDM4EMEN1KMT2ARAB9A
SCHEMBL20169535 0.72 PKM (0.37) KMT2AP2RX4MAPTBCHE
SCHEMBL11401928 0.72 DPP8 (0.53) DPP8DPP9DPP7RAB9ANPC1
SCHEMBL10192159 0.71 NOTUM (0.64) NOTUMKDM4EMEN1KMT2AHSD17B10
SCHEMBL5022144 0.70 HSD17B10 (0.44) NOTUMKDM4EMEN1KMT2AHSD17B10
SCHEMBL12559522 0.64 NOTUM (0.64) NOTUMKDM4EMEN1KMT2AMAPT
SCHEMBL26763831 0.64 MEN1 (0.54) NOTUMKDM4EMEN1KMT2AMAPT
SCHEMBL429841 0.63 NOTUM (0.76) NOTUMKDM4EMEN1KMT2ARAB9A
SCHEMBL20353827 0.63 HSD17B10 (0.43) MEN1KMT2AHSD17B10AADATMAPT
SCHEMBL25463664 0.63 NOTUM (0.53) NOTUMKDM4EMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249480-A1 DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Northwest A&F University (CN) 2023-09-27 EP disclosed