Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866824 | 0.82 | CHEK1 (0.42) | PDPK1YTHDC1CHEK1AURKAYTHDF2 | |
| SCHEMBL24409449 | 0.80 | NUDT1 (0.32) | CHEK1AURKA | |
| SCHEMBL19969968 | 0.71 | LIMK1 (0.33) | — | |
| SCHEMBL18526510 | 0.69 | CYP1A2 (0.31) | PDPK1 | |
| SCHEMBL5565234 | 0.69 | PDPK1 (0.44) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL18520486 | 0.67 | PDPK1 (0.42) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL26317506 | 0.67 | — | — | |
| SCHEMBL766829 | 0.66 | GALR3 (0.49) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL27739308 | 0.66 | PDPK1 (0.41) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL2491613 | 0.66 | PDPK1 (0.41) | PDPK1YTHDC1YTHDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303613-A1 | 3′3′ CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR, V.V.I. (CZ) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303613-A1 | 3′3′ CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | STING1, CGAS, IRF3 | PDPK1 497/4885YTHDC1 3243/4885CHEK1 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.