Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621311 | 0.86 | KMT2A (0.46) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| SCHEMBL1291311 | 0.86 | KMT2A (0.46) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| Hydrochloric Acid SCHEMBL30468480 | 0.84 | KMT2A (0.45) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| Hydrochloric Acid SCHEMBL15333616 | 0.84 | KMT2A (0.45) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| SCHEMBL16570034 | 0.83 | KMT2A (0.44) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| SCHEMBL28040740 | 0.83 | KMT2A (0.44) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| SCHEMBL10229066 | 0.82 | KMT2A (0.49) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| SCHEMBL7129087 | 0.79 | TAAR1 (0.41) | TAAR1ALDH1A1HTR2A | |
| Acetic Acid SCHEMBL1626987 | 0.79 | KMT2A (0.48) | KMT2ACLK2AURKBCLK4CYP19A1 | |
| SCHEMBL646500 | 0.79 | KMT2A (0.50) | KMT2ACLK2AURKBCLK4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438066-A2 | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a]PYRIDINE DERIVATIVES | Cephalon, Inc. (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010141796-A2 | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES | CEPHALON, INC. (US) | 2010-12-09 | — | — | WO | disclosed |