⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197588 | 0.83 | — | — | |
| SCHEMBL17653495 | 0.81 | HDAC4 (0.34) | — | |
| SCHEMBL11952530 | 0.81 | HDAC4 (0.34) | — | |
| SCHEMBL4578689 | 0.81 | HDAC4 (0.34) | — | |
| SCHEMBL11052535 | 0.81 | — | — | |
| SCHEMBL19743485 | 0.81 | TRPA1 (0.33) | — | |
| SCHEMBL19743486 | 0.81 | TRPA1 (0.33) | — | |
| SCHEMBL17653494 | 0.81 | HDAC4 (0.34) | — | |
| SCHEMBL20542554 | 0.81 | HDAC4 (0.34) | — | |
| SCHEMBL8521408 | 0.81 | TRPA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540712-A | A kind of modified phosphazene compound, Preparation method and use | 广东广山新材料股份有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-107540713-A | Low dielectric phosphazene compound, the Preparation method and use of a kind of modification | 广东广山新材料股份有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-117736207-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| US-11753385-B2 | Method for producing kakeromycin and derivatives thereof | OP BIO FACTORY CO., LTD. (JP) | 2023-09-12 | — | — | US | disclosed |
| CN-115160248-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-10-11 | — | — | CN | disclosed |
| CN-114874131-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-08-09 | — | — | CN | disclosed |
| CN-114835596-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-08-02 | — | — | CN | disclosed |
| CN-107709335-B | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-05-31 | — | — | CN | disclosed |
| US-20220024883-A1 | METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF | OP BIO FACTORY CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| WO-1996010014-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-04 | — | — | WO | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4438277-A | Hydronaphthalene derivatives | SANKYO COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4361515-A | Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1982-11-30 | — | — | US | disclosed |