Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171433 | 0.91 | MEN1 (0.47) | KMT2AMEN1GAAFOXO1CASP3 | |
| SCHEMBL4171436 | 0.91 | MEN1 (0.47) | KMT2AMEN1GAAFOXO1CASP3 | |
| SCHEMBL263135 | 0.83 | MEN1 (0.47) | KMT2AMEN1GAACNR1CNR2 | |
| SCHEMBL263554 | 0.83 | MEN1 (0.46) | KMT2AMEN1GAAFOXO1CASP3 | |
| SCHEMBL4170455 | 0.82 | MEN1 (0.49) | KMT2AMEN1GAACNR1FOXO1 | |
| SCHEMBL14248546 | 0.81 | MEN1 (0.48) | KMT2AMEN1GAAFOXO1RAB9A | |
| SCHEMBL27763824 | 0.79 | KMT2A (0.48) | KMT2AMEN1GAAFOXO1CASP3 | |
| SCHEMBL263553 | 0.78 | MEN1 (0.47) | KMT2AMEN1GAAFOXO1ALOX15 | |
| SCHEMBL9277340 | 0.78 | GAA (0.48) | KMT2AMEN1GAAFOXO1LMNA | |
| SCHEMBL262802 | 0.78 | MEN1 (0.48) | KMT2AMEN1GAAFOXO1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1995240-B1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-02-22 | — | — | EP | disclosed |