Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305020 | 0.88 | GSK3B (0.70) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL29249309 | 0.88 | KMT2A (0.62) | HAO1GSK3BCES1MEN1KMT2A | |
| SCHEMBL751516 | 0.84 | HPGD (0.74) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL28037967 | 0.83 | HAO1 (0.89) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL9352579 | 0.81 | TSHR (0.60) | CES1CES2MEN1KMT2AHPGD | |
| SCHEMBL11060497 | 0.80 | OGG1 (0.63) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL394576 | 0.80 | GSK3B (0.59) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL100952 | 0.80 | NR4A2 (0.65) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL10649708 | 0.79 | HAO1 (0.61) | HAO1GSK3BHDAC1HDAC8HDAC3 | |
| SCHEMBL28972855 | 0.79 | KMT2A (0.65) | HAO1GSK3BHDAC1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503601-A | The method of level-one amine guiding building 6- (4- bromophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-03-22 | — | — | CN | claimed |
| CN-105503945-B | A kind of method for preparing the Dicarbonyl derivatives of 2 phosphonate group 1,3 | 苏州大学 | 2017-09-05 | — | — | CN | claimed |
| CN-105503945-A | Method for preparing 2-phosphonic acid ester base-1, 3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | claimed |
| WO-2024210074-A1 | BENZOYLFORMIC ACID AMIDE DERIVATIVE | ＫＪケミカルズ株式会社 | 2024-10-10 | — | — | WO | disclosed |
| CN-118598836-A | Method for asymmetrically synthesizing chiral trans-3, 4-dihydrocoumarin derivative | 中北大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-109503601-A | The method of level-one amine guiding building 6- (4- bromophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-109503601-A | The method of level-one amine guiding building 6- (4- bromophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-105503945-B | A kind of method for preparing the Dicarbonyl derivatives of 2 phosphonate group 1,3 | 苏州大学 | 2017-09-05 | — | — | CN | disclosed |
| CN-104447707-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2017-04-12 | — | — | CN | disclosed |
| US-20160280653-A1 | QUINOLINES DERIVATIVES AS NOVEL ANTICANCER AGENTS | GENOSCIENCE PHARMA (FR) | 2016-09-29 | — | — | US | disclosed |
| CN-105503945-A | Method for preparing 2-phosphonic acid ester base-1, 3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | disclosed |
| WO-2012003164-A1 | BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100311799-A1 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141761-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0412933-B1 | Coating compositions | CIBA GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |
| US-5183842-A | Mixture of ketoacid and amine with film-forming binder, curing | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| US-5128396-A | Corrosion inhibiting primers on metallic substrates | CIBA-GEIGY CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0412933-A1 | Coating compositions | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280653-A1 | QUINOLINES DERIVATIVES AS NOVEL ANTICANCER AGENTS | NQO2, MKI67, NQO1 | HAO1 4252/4885GSK3B 674/4885HDAC1 881/4885 |
| US-20100311799-A1 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | LPAR1, LPAR2, LPAR4 | HAO1 1636/4885GSK3B 3416/4885HDAC1 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.