Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.88 |
| ▸ | BTK | Q06187 | 6/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.88 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.88 |
| ▸ | ESR1 | P03372 | 1/20 | 0.88 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.88 |
| ▸ | HTR1A | P08908 | 1/20 | 0.88 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.88 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.88 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.88 |
| ▸ | DRD1 | P21728 | 1/20 | 0.88 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.88 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.88 |
| ▸ | PDE4A | P27815 | 1/20 | 0.88 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.88 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.88 |
| ▸ | DRD3 | P35462 | 1/20 | 0.88 |
| ▸ | KDR | P35968 | 1/20 | 0.88 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.88 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Olmutinib SCHEMBL29358219 | 0.94 | EGFR (1.00) | EGFRBTKKCNH2ABCB11ESR1 | |
| Olmutinib SCHEMBL14914931 | 0.94 | EGFR (1.00) | EGFRBTKKCNH2ABCB11ESR1 | |
| Olmutinib SCHEMBL29377940 | 0.94 | EGFR (1.00) | EGFRBTKKCNH2ABCB11ESR1 | |
| Olmutinib SCHEMBL19643039 | 0.93 | EGFR (0.98) | EGFRBTKKCNH2ABCB11ESR1 | |
| Olmutinib SCHEMBL29786076 | 0.93 | EGFR (0.98) | EGFRBTKKCNH2ABCB11ESR1 | |
| SCHEMBL14914610 | 0.93 | EGFR (0.89) | EGFRBTKKCNH2ABCB11ESR1 | |
| SCHEMBL14914912 | 0.92 | EGFR (0.88) | EGFRBTKKCNH2ABCB11ESR1 | |
| SCHEMBL14914959 | 0.92 | EGFR (0.87) | EGFRBTKKCNH2ABCB11ESR1 | |
| SCHEMBL14915258 | 0.92 | EGFR (0.87) | EGFRBTKKCNH2ABCB11ESR1 | |
| SCHEMBL14916200 | 0.91 | EGFR (0.88) | EGFRBTKKCNH2ABCB11ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | KIT, HCCS, PPIF | EGFR 1166/4885BTK 3765/4885KCNH2 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.