SCHEMBL2636258

SCHEMBL2636258

C[C@]1(O)CC[C@@H]2C(C(=O)O)=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]21

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.61
▸ POLB P06746 1/20 0.52
▸ CTDSP1 Q9GZU7 1/20 0.52
▸ STAT3 P40763 14/20 0.49
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9056451 0.90 POLB (0.62) MAPTPOLBCTDSP1STAT3MEN1
SCHEMBL29425982 0.90 POLB (0.62) MAPTPOLBCTDSP1STAT3MEN1
SCHEMBL29425841 0.85 POLB (0.46) MAPTPOLBCTDSP1STAT3MEN1
SCHEMBL29426070 0.84 AKR1B1 (0.45) MAPTPOLBCTDSP1STAT3MEN1
Negundoside SCHEMBL381311 0.84 HSP90AA1 (0.48) MAPTPOLBCTDSP1STAT3
SCHEMBL9058007 0.84 POLB (0.46) MAPTPOLBCTDSP1STAT3MEN1
SCHEMBL29426237 0.84 MAPT (0.63) MAPTPOLBCTDSP1STAT3MEN1
Shanzhiside SCHEMBL306203 0.82 MAPT (0.58) MAPTPOLBCTDSP1STAT3MEN1
SCHEMBL29425733 0.81 MAPT (0.56) MAPTPOLBCTDSP1STAT3MEN1
SCHEMBL31179880 0.80 POLB (0.64) MAPTPOLBCTDSP1STAT3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4188075-A1 NUTRIENT LOSS REDUCTION METHOD, USES AND PRODUCTS PGG Wrightson Seeds Limited (NZ) 2023-06-07 — — EP claimed
WO-2022025774-A1 NUTRIENT LOSS REDUCTION METHOD, USES AND PRODUCTS PGG WRIGHTSON SEEDS LIMITED (NZ) 2022-02-03 — — WO claimed
US-7259148-B2 Hepatoprotective activity of 2′-p-hydroxybenzoylmussaenosidic acid COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-08-21 — — US claimed
CN-1658865-A Hepatoprotective activity of 10-o-p-hydroxybenzoyiaucubin COUNCIL SCIENT IND RES (IN) 2005-08-24 — — CN claimed
EP-1509223-A1 HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN Council Of Scientific And Industrial Research (IN) 2005-03-02 — — EP claimed
EP-1503773-A1 HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID Council of Scientific and Industrial Research (IN) 2005-02-09 — — EP claimed
US-20040029816-A1 Hepatoprotective activity of 10-O-P-hydroxybenzoyiaucubin COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2004-02-12 — — US claimed
US-20040014684-A1 Hepatoprotective activity of 2'-p-hydroxybenzoylmussaenosidic COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-01-22 — — US claimed
WO-2003094946-A1 HEPATOPROTECTIVE ACTIVITY OF 2'-P-HYDROXYBENZOYLMUSSAENOSIDIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 — — WO claimed
WO-2003094911-A1 HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 — — WO claimed
EP-4702037-A1 METHOD OF PRODUCING IRIDOIDS Nicoventures Trading Limited (GB) 2026-03-04 — — EP disclosed
WO-2024224085-A1 METHOD OF PRODUCING IRIDOIDS Nicoventures Trading Limited (GB) 2024-10-31 — — WO disclosed
EP-4188075-A1 NUTRIENT LOSS REDUCTION METHOD, USES AND PRODUCTS PGG Wrightson Seeds Limited (NZ) 2023-06-07 — — EP disclosed
EP-3409766-B1 AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS N ZYME BIOTEC GMBH (DE) 2022-03-09 — — EP disclosed
WO-2022025774-A1 NUTRIENT LOSS REDUCTION METHOD, USES AND PRODUCTS PGG WRIGHTSON SEEDS LIMITED (NZ) 2022-02-03 — — WO disclosed
US-20040014684-A1 Hepatoprotective activity of 2'-p-hydroxybenzoylmussaenosidic COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-01-22 — — US disclosed
US-20040014684-A1 Hepatoprotective activity of 2'-p-hydroxybenzoylmussaenosidic COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-01-22 — — US disclosed
WO-2003094946-A1 HEPATOPROTECTIVE ACTIVITY OF 2'-P-HYDROXYBENZOYLMUSSAENOSIDIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 — — WO disclosed
WO-2003094946-A1 HEPATOPROTECTIVE ACTIVITY OF 2'-P-HYDROXYBENZOYLMUSSAENOSIDIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 — — WO disclosed
WO-2003094911-A1 HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 — — WO disclosed
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