Negundoside

Negundoside

SCHEMBL381311

C[C@]1(O)CC[C@@H]2C(C(=O)O)=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3OC(=O)c3ccc(O)cc3)[C@@H]21

nearest known ligand 0.48

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 4/20 0.48
▸ MAPT P10636 1/20 0.45
▸ POLB P06746 1/20 0.42
▸ CTDSP1 Q9GZU7 1/20 0.42
▸ STAT3 P40763 8/20 0.40
▸ JUN P05412 2/20 0.38
▸ EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29426039 0.86 AKR1B1 (0.41) HSP90AA1MAPTPOLBCTDSP1STAT3
SCHEMBL2636258 0.84 MAPT (0.61) MAPTPOLBCTDSP1STAT3
SCHEMBL29426091 0.83 CYP19A1 (0.44) HSP90AA1EPHX2
SCHEMBL29426070 0.81 AKR1B1 (0.45) MAPTPOLBCTDSP1STAT3EPHX2
SCHEMBL29425982 0.78 POLB (0.62) MAPTPOLBCTDSP1STAT3
SCHEMBL9056451 0.78 POLB (0.62) MAPTPOLBCTDSP1STAT3
SCHEMBL29425841 0.71 POLB (0.46) HSP90AA1MAPTPOLBCTDSP1STAT3
SCHEMBL31179884 0.70 HSP90AA1 (0.55) HSP90AA1MAPTPOLBCTDSP1
SCHEMBL31179879 0.70 HSP90AA1 (0.55) HSP90AA1MAPTPOLBCTDSP1
SCHEMBL9058007 0.70 POLB (0.46) HSP90AA1MAPTPOLBCTDSP1STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025524-A1 HERBAL COMPOSITION AND METHOD FOR TREATING OR PREVENTING ACUTE OR CHRONIC PAIN ENOVATE BIOLIFE PVT. LTD. (IN) 2025-01-23 — — US disclosed
EP-1503773-B9 HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID COUNCIL SCIENT IND RES (IN) 2012-01-25 — — EP disclosed
EP-1503773-B1 HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID COUNCIL SCIENT IND RES (IN) 2011-03-30 — — EP disclosed
CN-100512811-C Hepatoprotective activity of 10-O-p-hydroxybenzoyl aucubin COUNCIL SCIENT IND RES (IN) 2009-07-15 — — CN disclosed
CN-100391465-C Hepatoprotective activity of 2' -p-hydroxybenzoylmussaenosidic acid COUNCIL SCIENT IND RES (IN) 2008-06-04 — — CN disclosed
US-7259148-B2 Hepatoprotective activity of 2′-p-hydroxybenzoylmussaenosidic acid COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-08-21 — — US disclosed
CN-1658865-A Hepatoprotective activity of 10-o-p-hydroxybenzoyiaucubin COUNCIL SCIENT IND RES (IN) 2005-08-24 — — CN disclosed
CN-1652808-A Hepatoprotective activity of 2' -p-hydroxybenzoylmussaenosidic acid COUNCIL SCIENT IND RES (IN) 2005-08-10 — — CN disclosed
EP-1503773-A1 HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID Council of Scientific and Industrial Research (IN) 2005-02-09 — — EP disclosed
US-20040014684-A1 Hepatoprotective activity of 2'-p-hydroxybenzoylmussaenosidic COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-01-22 — — US disclosed
WO-2003094946-A1 HEPATOPROTECTIVE ACTIVITY OF 2'-P-HYDROXYBENZOYLMUSSAENOSIDIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 — — WO disclosed
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