Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636406 | 1.00 | CXCL12 (0.53) | CXCL12ABCG2MEN1KMT2AMKNK2 | |
| SCHEMBL28048505 | 0.83 | KMT2A (0.47) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4254456 | 0.82 | ABCG2 (0.67) | CXCL12ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL4254451 | 0.82 | ABCG2 (0.67) | CXCL12ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL5692902 | 0.80 | CXCL12 (0.79) | CXCL12ABCG2MEN1KMT2AXDH | |
| SCHEMBL5692905 | 0.80 | CXCL12 (0.79) | CXCL12ABCG2MEN1KMT2AXDH | |
| SCHEMBL5693342 | 0.78 | PKM (0.61) | CXCL12MEN1KMT2AMKNK2XDH | |
| SCHEMBL5693344 | 0.78 | PKM (0.61) | CXCL12MEN1KMT2AMKNK2XDH | |
| SCHEMBL2636878 | 0.77 | CXCL12 (0.56) | CXCL12ABCG2MEN1KMT2AMKNK2 | |
| SCHEMBL4576554 | 0.77 | CXCL12 (0.52) | CXCL12ABCG2MEN1KMT2AMKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2437792-B1 | IMAGING OF MYELIN BASIC PROTEIN | GEN ELECTRIC (US) | 2015-10-21 | — | — | EP | disclosed |
| US-8617515-B2 | Imaging of myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2437792-A2 | IMAGING OF MYELIN BASIC PROTEIN | General Electric Company (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010141704-A2 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100310457-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310457-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | CXCL12 2457/4885ABCG2 4452/4885MEN1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.