SCHEMBL26370481

SCHEMBL26370481

Cc1cn2c3c(cccc3c1=O)CC2

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
PARP1 P09874 1/20 0.44
MTNR1A P48039 5/20 0.41
MTNR1B P49286 5/20 0.41
OPA1 O60313 1/20 0.39
EIF5B O60841 1/20 0.39
MET P08581 1/20 0.39
HMOX2 P30519 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23221087 0.92 HPGD (0.55) HPGDUSP2ALDH1A1HSD17B10HTR2A
SCHEMBL10100276 0.78 HTR2A (0.59) HPGDUSP2ALDH1A1HSD17B10MEN1
SCHEMBL5434419 0.77 MCL1 (0.41) LMNAKMT2AHTR2AHTR2CPARP1
SCHEMBL17553683 0.77 HTR2A (0.54) HPGDUSP2ALDH1A1HSD17B10MEN1
SCHEMBL6837082 0.76 MEN1 (0.41) MEN1KMT2AHTR2AHTR2CPARP1
SCHEMBL5434257 0.76 KDM4E (0.54) USP2ALDH1A1LMNATDP1MTNR1A
SCHEMBL21648579 0.74 MCL1 (0.46) HTR2AHTR2CPARP1MCL1
SCHEMBL22096079 0.74 HTR2A (0.45) HPGDUSP2ALDH1A1HSD17B10MEN1
SCHEMBL25030544 0.72 MEN1 (0.42) HPGDUSP2ALDH1A1HSD17B10MEN1
SCHEMBL8039755 0.72 HTR2A (0.49) HPGDUSP2ALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158862-A2 STIMULATOR OF INTERFERON GENES (STING) MODULATORS, AND COMPOSITIONS AND METHODS THEREOF GEODE THERAPEUTICS INC. (US) 2023-08-24 WO disclosed