Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232733 | 0.81 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL24045549 | 0.77 | HSD17B10 (0.39) | CYP2C19 | |
| SCHEMBL17229749 | 0.77 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL16127913 | 0.70 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL21334031 | 0.69 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL17234780 | 0.67 | HSD17B10 (0.39) | CYP2C19 | |
| SCHEMBL17229819 | 0.67 | CYP2C19 (0.37) | CYP2C19 | |
| SCHEMBL12719797 | 0.59 | KDM4E (0.55) | CYP2C19 | |
| SCHEMBL791613 | 0.58 | — | — | |
| SCHEMBL20517731 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312585-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312585-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HRH4, HRH3, HRH2 | CYP2C19 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.