SCHEMBL26374

SCHEMBL26374

O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.65
BCL9 O00512 1/20 0.61
CTNNB1 P35222 1/20 0.61
KMT2A Q03164 3/20 0.59
PKM P14618 1/20 0.59
HTR2A P28223 1/20 0.55
CES1 P23141 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CES2 O00748 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
ALDH1A1 P00352 2/20 0.54
MAPT P10636 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
MAPK1 P28482 1/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
MYOC Q99972 1/20 0.53
MGLL Q99685 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7895043 0.98 GAA (0.62) GAABCL9CTNNB1KMT2APKM
SCHEMBL1639306 0.94 GAA (0.59) GAABCL9CTNNB1KMT2APKM
Ethylene Glycol SCHEMBL5476146 0.92 BCL9 (0.58) GAABCL9CTNNB1KMT2APKM
SCHEMBL26654348 0.92 GAA (0.57) GAABCL9CTNNB1KMT2APKM
SCHEMBL20377184 0.92 SMN1; SMN2 (0.64) GAABCL9CTNNB1KMT2APKM
Acetic Acid SCHEMBL28965272 0.92 GAA (0.62) GAABCL9CTNNB1KMT2APKM
SCHEMBL6322393 0.92 SMN1; SMN2 (0.64) GAABCL9CTNNB1KMT2APKM
SCHEMBL14378853 0.92 GAA (0.61) GAABCL9CTNNB1KMT2APKM
SCHEMBL3176066 0.92 GAA (0.61) GAABCL9CTNNB1KMT2APKM
SCHEMBL14308548 0.91 KMT2A (0.73) GAABCL9CTNNB1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17602 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124318-A1 POLYMERIC MATERIAL AND PREPARATION METHOD THEREOF, AND DRUG-LOADING MATERIAL SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2026-05-07 US claimed
EP-4201429-B1 ANTIBODY-DRUG CONJUGATE INTERMEDIATE COMPRISING SN38 AND PREPARATION METHOD THEREFOR MABPLEX INT CO LTD (CN) 2026-05-06 EP claimed
US-12600825-B2 Polymer compositions and biosurfaces comprising them on sensors ZEPTO LIFE TECHNOLOGY, INC. (US) 2026-04-14 US claimed
US-20260060921-A1 HYDROGEL DRUG DELIVERY IMPLANTS INCEPT LLC (US) 2026-03-05 US claimed
EP-4702992-A1 ANTIBODY-DRUG CONJUGATE CSPC Megalith Biopharmaceutical Co., Ltd. (CN) 2026-03-04 EP claimed
US-12558431-B2 Method of preparing protein conjugate HANMI PHARM. CO., LTD. (KR) 2026-02-24 US claimed
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
EP-4389744-B1 DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2025-12-03 EP claimed
EP-3993130-B1 LITHIUM-SULFUR BATTERY ELECTROLYTE AND LITHIUM-SULFUR BATTERY COMPRISING SAME LG ENERGY SOLUTION LTD (KR) 2025-11-26 EP claimed
WO-2025227129-A2 DELIVERY VEHICLES COMPRISING PROGLUCAGON DERIVED POLYPEPTIDES AND ANABOLIC POLYPEPTIDES AND USES THEREOF STARROCK PHARMA LLC (US) 2025-10-30 WO claimed
EP-0295073-B1 Chromatographic material CHROMATOCHEM INC (US) 1997-03-12 EP claimed
WO-1996000080-A1 NON-ANTIGENIC AMINE DERIVED POLYMERS AND POLYMER CONJUGATES ENZON, INC. (US) 1996-01-04 WO claimed
US-5446134-A Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1995-08-29 US claimed
WO-1995011924-A1 NON-ANTIGENIC BRANCHED POLYMER CONJUGATES ENZON, INC. (US) 1995-05-04 WO claimed
EP-0624377-A2 Lysosomal enzyme-cleavable antitumor drug conjugates Bristol-Myers Squibb Company (US) 1994-11-17 EP claimed
US-5240602-A Silica solid-support-polyethylene glycol binder-hydrophilic spacer activated coupler ligand CHROMATOCHEM, INC. (US) 1993-08-31 US claimed
US-4596680-A Heating in the presence of basic catalyst two aryl carbonates INSTITUT FRANCAIS DU PETROLE (FR) 1986-06-24 US claimed
EP-0091851-B1 PROCESS FOR PREPARING ARYL ETHERS CARRYING DIFFERENT SUBSTITUENTS ON THE TWO AROMATIC NUCLEI Institut Français du Pétrole (FR) 1986-02-19 EP claimed
EP-0091851-A1 Process for preparing aryl ethers carrying different substituents on the two aromatic nuclei Institut Français du Pétrole (FR) 1983-10-19 EP claimed
US-4101569-A Process for the preparation of 4,4'-dinitrodiphenyl carbonate BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US claimed