Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377184 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1ALOX5GAACES2 | |
| SCHEMBL26374 | 0.92 | GAA (0.65) | SMN1; SMN2ALDH1A1GAACES2CES1 | |
| SCHEMBL17022709 | 0.91 | POLB (0.63) | SMN1; SMN2ALDH1A1ALOX5GAACES2 | |
| Hydrochloric Acid SCHEMBL7895043 | 0.90 | GAA (0.62) | SMN1; SMN2ALDH1A1GAACES2CES1 | |
| SCHEMBL26654348 | 0.89 | GAA (0.57) | SMN1; SMN2ALDH1A1GAACES2CES1 | |
| Acetic Acid SCHEMBL28965272 | 0.89 | GAA (0.62) | SMN1; SMN2ALDH1A1GAABCL9CTNNB1 | |
| SCHEMBL8741192 | 0.89 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1ALOX5GAACES2 | |
| SCHEMBL29769770 | 0.88 | ALOX5 (0.65) | SMN1; SMN2ALDH1A1ALOX5GAAKDM4E | |
| SCHEMBL1639306 | 0.87 | GAA (0.59) | SMN1; SMN2ALDH1A1GAACES2CES1 | |
| SCHEMBL27421509 | 0.87 | ALOX5 (0.60) | SMN1; SMN2ALDH1A1ALOX5GAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409723-B1 | POLYCARBONATE RESIN COMPOSITION, HEAT RAY-SHIELDING MOLDED ARTICLE, AND HEAT RAY-SHIELDING LAMINATE | SUMITOMO METAL MINING CO (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20230128167-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | MABPLEX INTERNATIONAL, LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-11618731-B2 | Prodrugs of kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-04-04 | — | — | US | disclosed |
| EP-3532057-B1 | PRODRUGS OF KALLIKREIN INHIBITORS | BIOCRYST PHARM INC (US) | 2022-12-21 | — | — | EP | disclosed |
| US-20210198204-A1 | PRODRUGS OF KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2021-07-01 | — | — | US | disclosed |
| US-10759759-B2 | Prodrugs of kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2020-09-01 | — | — | US | disclosed |
| US-10676612-B2 | Polycarbonate resin composition, heat ray shielding molded body and heat ray shielding lamination body | SUMITOMO METAL MINING CO., LTD. (JP) | 2020-06-09 | — | — | US | disclosed |
| EP-3532057-A1 | PRODRUGS OF KALLIKREIN INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2019-09-04 | — | — | EP | disclosed |
| US-20190040251-A1 | POLYCARBONATE RESIN COMPOSITION, HEAT RAY SHIELDING MOLDED BODY AND HEAT RAY SHIELDING LAMINATION BODY | SUMITOMO METAL MINING CO., LTD. (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-3409723-A1 | POLYCARBONATE RESIN COMPOSITION, HEAT RAY-SHIELDING MOLDED ARTICLE, AND HEAT RAY-SHIELDING LAMINATE | Sumitomo Metal Mining Co., Ltd. (JP) | 2018-12-05 | — | — | EP | disclosed |
| US-6908655-B2 | Optical recording medium | SONY CORPORATION (JP) | 2005-06-21 | — | — | US | disclosed |
| CN-1198876-C | optical polycarbonate resin molding material and optical disk substrate | TEIJIN CHEMICALS LTD (JP) | 2005-04-27 | — | — | CN | disclosed |
| CN-1478084-A | Compounds useful in treatment of inflammatory diseases | — | 2004-02-25 | — | — | CN | disclosed |
| CN-1427871-A | Aromatic polycarbonate resin composition | TEIJIN CHEMICALS LTD (JP) | 2003-07-02 | — | — | CN | disclosed |
| CN-1408767-A | Flame retardant aromatic poly cabonic ester resin composition and finished products | TEIJIN CHEMICAL CO LTD (JP) | 2003-04-09 | — | — | CN | disclosed |
| CN-1361765-A | Aspartyl protease inhibitors | VERTEX PHARMA (US) | 2002-07-31 | — | — | CN | disclosed |
| US-20010044004-A1 | Optical recording medium | SONY CORPORATION (JP) | 2001-11-22 | — | — | US | disclosed |
| CN-1323331-A | Polycarbonate resin molding material for optical use and optical disk substrate | TEIJIN CHEMICALS LTD (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1130587-A2 | Optical recording medium | SONY CORPORATION (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5488089-A | Curable resin composition | KANSAI PAINT CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128167-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | VIP, DNPEP, PREP | SMN1; SMN2 1997/4885ALDH1A1 4667/4885ALOX5 4287/4885 |
| US-20210198204-A1 | PRODRUGS OF KALLIKREIN INHIBITORS | KLKB1, SERPINB1, KLK1 | SMN1; SMN2 3706/4885ALDH1A1 1091/4885ALOX5 788/4885 |
| US-11618731-B2 | Prodrugs of kallikrein inhibitors | KLKB1, SERPINB1, KLK1 | SMN1; SMN2 3706/4885ALDH1A1 1091/4885ALOX5 788/4885 |
| US-10759759-B2 | Prodrugs of kallikrein inhibitors | KLKB1, SERPINB1, KLK1 | SMN1; SMN2 3706/4885ALDH1A1 1091/4885ALOX5 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.