Chloroform

Chloroform

SCHEMBL263740

[2H]C(Cl)(Cl)Cl.[2H]CC#N

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL1594871 0.80
Chloroform SCHEMBL181824 0.68
Chloroform SCHEMBL613360 0.68
Chloroform SCHEMBL9236775 0.68 ALDH1A1 (0.46)
Chloroform SCHEMBL7827442 0.68 ALDH1A1 (0.46)
Chloroform SCHEMBL9230061 0.68 ALDH1A1 (0.46)
Chloroform SCHEMBL8518307 0.66
Chloroform SCHEMBL25366 0.66
Chloroform SCHEMBL10492441 0.65
Acetonitrile SCHEMBL365119 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133694-B2 Analyzing metabolites, binding proteins; cyanoalkylation; competitive binding; immunoassay; kits IMMUNDIAGNOSTIK AG (DE) 2012-03-13 US disclosed
US-20050014211-A1 Functional vitamin D derivatives and method of determining 25-hydroxy- and 1alpha, 25-dihydroxy vitamin D BIOMEDICA GMBH (AT) 2005-01-20 US disclosed
US-6787660-B1 CYANOETHYLATING 3-HYDROXY GROUP, REDUCING TO AMINE AND LINKING WITH SPACER CONTAINING FUNCTIONAL GROUP; COMPETITIVE PROTEIN BINDING ANALYSIS IMMUNDIAGNOSTIK AG (DE) 2004-09-07 US disclosed