SCHEMBL26374651

SCHEMBL26374651

c1ccc(-n2c3ccccc3c3c4c5c6ccccc6ccc5n(-c5cccc(-c6cccc7oc8ccccc8c67)c5)c4ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
KDM4E B2RXH2 3/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
ABCG2 Q9UNQ0 4/20 0.35
AHR P35869 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
FYN P06241 1/20 0.35
MAPK3 P27361 1/20 0.35
PAX8 Q06710 1/20 0.35
TSHR P16473 3/20 0.32
HSD17B10 Q99714 3/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26374636 1.00 SIRT2 (0.36) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL26476492 0.94 L3MBTL1 (0.37) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL22926991 0.93 TDP1 (0.40) SIRT2SIRT1L3MBTL1KDM4ETDP1
SCHEMBL24230899 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMTSHRHSD17B10
SCHEMBL22186621 0.92 SIRT2 (0.34) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL23960989 0.92 SIRT2 (0.34) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL26476746 0.91 L3MBTL1 (0.37) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL23874732 0.90 KDM4E (0.34) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL26374631 0.90 TP53 (0.32) SIRT2SIRT1L3MBTL1KDM4EATM
SCHEMBL23960918 0.90 SIRT2 (0.33) SIRT2SIRT1L3MBTL1TDP1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed