Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959350 | 0.84 | TSHR (0.36) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL23961062 | 0.84 | TSHR (0.36) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL23961111 | 0.83 | TSHR (0.37) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL23959352 | 0.83 | TSHR (0.37) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL26374992 | 0.76 | KMT2A (0.38) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL12533279 | 0.76 | KMT2A (0.51) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL1766747 | 0.76 | KMT2A (0.51) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL1766751 | 0.76 | KMT2A (0.51) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL23961047 | 0.76 | KMT2A (0.51) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL23959329 | 0.74 | KMT2A (0.54) | MEN1KMT2ATSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4252755-A2 | THERAPEUTIC COMPOUNDS | C4x Discovery Limited (GB) | 2023-10-04 | — | — | EP | disclosed |