SCHEMBL26375366

SCHEMBL26375366

Cc1cc(C(F)(F)F)ccc1-c1ccc(F)cc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.41
MPL P40238 1/20 0.41
GPBAR1 Q8TDU6 3/20 0.40
NR1D1 P20393 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
MCL1 Q07820 2/20 0.40
APP P05067 1/20 0.40
PDE2A O00408 2/20 0.39
PDE10A Q9Y233 1/20 0.39
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP11B2 P19099 2/20 0.39
CYP11B1 P15538 1/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21131180 0.84 CYP1A2 (0.47) MAPTPDE2ACYP1A2
SCHEMBL27632453 0.81 HSD11B1 (0.48) HSD11B1MPLGPBAR1MAPTPDE2A
SCHEMBL24910274 0.80 PDE2A (0.45) HSD11B1MPLGPBAR1POLBMAPT
SCHEMBL14113002 0.79 PPARA (0.45) POLBMAPTMCL1APPCYP1A2
SCHEMBL30069362 0.79 MEN1 (0.46) MAPTPDE3BPDE3A
SCHEMBL12627935 0.79 MEN1 (0.46) MAPTPDE3BPDE3A
SCHEMBL16900276 0.77 APP (0.57) APPALOX5APFEN1CYP1A1CYP1B1
SCHEMBL21122207 0.76 NOTUM (0.49) PDE2APDE10ACYP1A2
SCHEMBL26375358 0.75 PDE3B (0.44) CYP1A2PDE3BPDE3A
SCHEMBL10094452 0.75 PDE2A (0.51) HSD11B1MPLAPPPDE2AALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 HSD11B1 608/4885MPL 3262/4885GPBAR1 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.