SCHEMBL26375421

SCHEMBL26375421

Cc1cc(-c2cccc(C(F)(F)F)c2)ccc1C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.47
KDM1A O60341 1/20 0.46
KIF11 P52732 1/20 0.45
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
IKBKB O14920 1/20 0.44
PGR P06401 1/20 0.44
BRD4 O60885 1/20 0.44
ASIC3 Q9UHC3 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
AR P10275 1/20 0.43
PTPN5 P54829 1/20 0.43
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.41
IDO1 P14902 1/20 0.41
NOTUM Q6P988 1/20 0.41
PDE2A O00408 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375437 0.86 S1PR1 (0.49) MAOBKDM1AKIF11SLC1A3SLC1A2
SCHEMBL26375476 0.85 RXRB (0.58) KIF11IKBKBRXRARXRBAR
SCHEMBL26375418 0.83 KIF11 (0.51) KIF11RXRARXRBARPDE2A
SCHEMBL27451573 0.83 KIF11 (0.48) KIF11RXRARXRBAR
SCHEMBL1538943 0.80 PDE2A (0.56) KIF11PTPN5RAPGEF4NOTUMPDE2A
SCHEMBL1263144 0.80 TSHR (0.58) MAOBKDM1AKIF11PGRASIC3
SCHEMBL29678302 0.80 TSHR (0.58) MAOBKDM1AKIF11PGRASIC3
SCHEMBL1044345 0.79 PTPN5 (0.63) MAOBKDM1AKIF11IKBKBPGR
SCHEMBL26375479 0.79 PDE2A (0.45) KIF11RXRARXRBARNOTUM
SCHEMBL26827704 0.78 MAOB (0.62) MAOBKDM1AKIF11PGRASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 MAOB 1919/4885KDM1A 1488/4885KIF11 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.