SCHEMBL26375481

SCHEMBL26375481

Cc1ccc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.49
GLA P06280 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.45
CES2 O00748 2/20 0.44
NFE2L2 Q16236 1/20 0.40
ABCC8 Q09428 1/20 0.39
KCNJ11 Q14654 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
GPR3 P46089 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2C9 P11712 1/20 0.38
SCN9A Q15858 1/20 0.38
PDE2A O00408 1/20 0.38
SYK P43405 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375489 0.91 KIF11 (0.45) KIF11GLAPOLBGAATSHR
SCHEMBL10030392 0.89 GLA (0.54) KIF11GLAPOLBGAATSHR
SCHEMBL28676412 0.87 TSHR (0.56) KIF11GLAPOLBGAATSHR
SCHEMBL26454263 0.85 KIF11 (0.41) KIF11GLAPOLBGAATSHR
SCHEMBL26375428 0.85 AKR1C3 (0.50) KIF11AKR1C3AKR1C2ALOX5APFEN1
SCHEMBL24017165 0.83 GLA (0.38) KIF11GLAPOLBGAATSHR
SCHEMBL26375442 0.82 NOTUM (0.45) KIF11GLAPOLBGAATSHR
SCHEMBL278789 0.82 GAA (0.47) GLAPOLBGAATSHRAKR1C3
SCHEMBL26375550 0.81 AKR1C3 (0.47) KIF11GLAPOLBGAATSHR
SCHEMBL26375483 0.81 AKR1C3 (0.43) KIF11GLAPOLBGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 KIF11 755/4885GLA 4070/4885POLB 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.