Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18551248 | 1.00 | HRH3 (0.36) | HRH3SMN1; SMN2EPHX1EPHX2CHRM3 | |
| SCHEMBL20046547 | 0.86 | PABPC1 (0.39) | HRH3EPHX1EPHX2CHRM3CARM1 | |
| SCHEMBL20323808 | 0.84 | HRH3 (0.36) | HRH3SMN1; SMN2EPHX1EPHX2CHRM3 | |
| SCHEMBL21026170 | 0.81 | HRH3 (0.40) | HRH3KDM4EMEN1KMT2ACARM1 | |
| SCHEMBL21341579 | 0.81 | POLB (0.33) | CARM1PRMT6 | |
| SCHEMBL23664698 | 0.81 | POLB (0.33) | CARM1PRMT6 | |
| SCHEMBL21933197 | 0.81 | HRH3 (0.34) | HRH3SMN1; SMN2EPHX1EPHX2CHRM3 | |
| SCHEMBL21471898 | 0.81 | HRH3 (0.34) | HRH3SMN1; SMN2EPHX1EPHX2CHRM3 | |
| SCHEMBL24508771 | 0.81 | KDM4E (0.36) | HRH3SMN1; SMN2EPHX1EPHX2CHRM3 | |
| SCHEMBL25123547 | 0.81 | NAMPT (0.36) | HRH3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689868-B1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS INC (US) | 2023-09-27 | — | — | EP | disclosed |