Fenclonine

Fenclonine

SCHEMBL26382

NC(Cc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.69
PTGS1 P23219 3/20 0.68
ALPI P09923 1/20 0.68
PKM P14618 1/20 0.68
XIAP P98170 1/20 0.68
HIF1A Q16665 5/20 0.58
CYP3A4 P08684 3/20 0.58
ALOX15 P16050 3/20 0.58
ALDH1A1 P00352 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
KDM4E B2RXH2 2/20 0.58
SLC6A3 Q01959 2/20 0.58
ABCB11 O95342 1/20 0.58
CHRM2 P08172 1/20 0.58
ADRA2A P08913 1/20 0.58
CHRM1 P11229 1/20 0.58
ACHE P22303 1/20 0.58
OPRM1 P35372 1/20 0.58
DRD3 P35462 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenclonine SCHEMBL245828 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL26383 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL3140768 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL6357978 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL16825893 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL988270 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL28422788 0.94 SLC7A5 (0.79) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL30722994 0.94 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL20714933 0.94 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL8497239 0.94 SLC7A5 (0.79) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10836 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035408-A1 WKYMVm peptide analogues having six residues and uses thereof RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR) 2026-02-05 US claimed
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
US-20250332223-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2025-10-30 US claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
US-20250304620-A1 ANTIMICROBIAL PEPTIDE AND APPLICATION THEREOF CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-10-02 US claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
US-12377135-B2 GHRH antagonists for use in a method of treating sarcoidosis UNIVERSITY OF MIAMI (US) 2025-08-05 US claimed
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-19 US claimed
EP-0076557-B1 PEPTIDES AND PSEUDOPEPTIDES IN WHICH THE N TERMINUS BEARS TWO SUBSTITUENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-13 EP claimed
EP-0161007-A2 Retro - inverso C-Terminal hexapeptide analogues of substance P ENI-Ente Nazionale Idrocarburi (IT) 1985-11-13 EP claimed
EP-0082568-B1 RETRO-INVERSO ANALOGUES OF C-TERMINAL PENTA AND HEXAPEPTIDES OF SUBSTANCE P. ANIC S.p.A. (IT) 1984-11-21 EP claimed
US-4444778-A ANTISEROTONINE AGENTS COUGHLIN SHAUN R 1984-04-24 US claimed
US-4439360-A Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P ANIC S.P.A. (IT) 1984-03-27 US claimed
US-4421744-A OPIATE RECEPTOR ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-20 US claimed
US-4407952-A OF GENETICALLY ENGINEERED ESCHERICHIA AJINOMOTO COMPANY INCORPORATED (JP) 1983-10-04 US claimed
EP-0082568-A2 Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. ANIC S.p.A. (IT) 1983-06-29 EP claimed
EP-0076557-A2 Peptides and pseudopeptides in which the N terminus bears two substituents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-13 EP claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed