SCHEMBL2638253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2639084	0.90	TSHR (0.38)	TSHRBTN3A1THRBALDH1A1
	SCHEMBL2638252	0.88	TSHR (0.39)	TSHRTHRBALDH1A1
	SCHEMBL3975681	0.85	LPAR3 (0.35)	TSHRLPAR3LPAR2LPAR1BTN3A1
	SCHEMBL288234	0.83	TSHR (0.44)	TSHRLPAR3LPAR1ALDH1A1PGD
	SCHEMBL17350353	0.83	TSHR (0.35)	TSHRTHRBALDH1A1
	SCHEMBL3411386	0.82	TSHR (0.42)	TSHRTHRBALDH1A1
	SCHEMBL991277	0.82	LPAR3 (0.33)	TSHRLPAR3LPAR2LPAR1BTN3A1
	SCHEMBL28788432	0.81	TSHR (0.43)	TSHRLPAR3LPAR1ALDH1A1PGD
	Ammonia Solution, Strong SCHEMBL18140024	0.81	TSHR (0.43)	TSHRLPAR3LPAR1ALDH1A1PGD
	SCHEMBL27898138	0.81	LPAR3 (0.36)	TSHRLPAR3LPAR2LPAR1BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.