Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639714 | 0.88 | HPGD (0.50) | ALDH1A1HPGDMEN1KMT2AKCNQ2 | |
| SCHEMBL2638875 | 0.85 | MEN1 (0.52) | ALDH1A1HPGDMEN1KMT2AKCNQ2 | |
| SCHEMBL2639288 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1KMT2ARORC | |
| SCHEMBL2638866 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1KMT2ARORC | |
| SCHEMBL2638268 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1KMT2ARORC | |
| SCHEMBL2639370 | 0.81 | MEN1 (0.51) | ALDH1A1HPGDMEN1KMT2AP2RX7 | |
| SCHEMBL2638392 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2ARORC | |
| SCHEMBL2638403 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1KMT2AKCNQ2 | |
| SCHEMBL2638808 | 0.80 | CA1 (0.54) | RORCSMN1; SMN2 | |
| SCHEMBL2640097 | 0.77 | MEN1 (0.54) | ALDH1A1HPGDMEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4810529-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1742908-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-11 | — | — | EP | claimed |
| EP-1742908-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-01-17 | — | — | EP | claimed |
| WO-2005102989-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-03 | — | — | WO | claimed |
| EP-1742908-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-11 | — | — | EP | disclosed |