SCHEMBL2638947

SCHEMBL2638947

N#Cc1cc(N)ccc1-c1ccc(N)cc1C#N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.55
ALDH1A1 P00352 6/20 0.55
USP2 O75604 1/20 0.55
LMNA P02545 3/20 0.52
MAPT P10636 4/20 0.48
HPGD P15428 4/20 0.48
CYP3A4 P08684 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
MDM4 O15151 1/20 0.41
GAA P10253 3/20 0.39
HSD17B10 Q99714 2/20 0.39
TSHR P16473 3/20 0.38
POLB P06746 2/20 0.38
GLA P06280 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21715760 0.88 KDM4E (0.51) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL21036120 0.88 KDM4E (0.46) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL30101062 0.87 KDM4E (0.48) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL22780766 0.83 KDM4E (0.53) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL30533023 0.83 KDM4E (0.53) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL8866253 0.83 KDM4E (0.45) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL27385133 0.83 TSHR (0.47) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL27297949 0.83 ALDH1A1 (0.49) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL21715781 0.83 KDM4E (0.44) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL204121 0.82 KDM4E (0.69) KDM4EALDH1A1USP2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0698052-B1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS UNIV AKRON (US) 2000-06-14 EP claimed
JP-H08511812-A 1996-12-10 JP claimed
US-5480964-A CONTROLLING ORIENTATION BY SUBSTITUTION ON AROMATIC BACKBONE THE UNIVERSITY OF AKRON (US) 1996-01-02 US claimed
US-5395918-A Heat resistance, electrical resistance and mechanical properties THE UNIVERSITY OF AKRON (US) 1995-03-07 US claimed
WO-1994024191-A1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS THE UNIVERSITY OF AKRON (US) 1994-10-27 WO claimed
US-5344916-A Multilayer films for optical displays using polyimide films THE UNIVERSITY OF AKRON (US) 1994-09-06 US claimed
US-7074493-B1 from 2,2'-bis(trifluoromethyl or trifluoromethylphenyl)-4,4'-diamino biphenyl and 2,2'-bis(trifluoromethyl or trifluoromethylphenyl)-3,3',4,4'-biphenyl tetracarboxylic acid; soluble in organic solvents; low dielectric constant; high coefficient of thermal expansion; heat resistance; integrated circuits THE UNIVERSITY OF AKRON (US) 2006-07-11 US disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed
WO-2000045435-A1 POLYIMIDES USED AS MICROELECTRONIC COATINGS THE UNIVERSITY OF AKRON (US) 2000-08-03 WO disclosed
EP-0698052-B1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS UNIV AKRON (US) 2000-06-14 EP disclosed
US-5491200-A FORMING GRAFT OR BLOCK COPOLYMER FROM POLYIMIDE ENDCAPPED WITH ACYL-ACTIVATED CAPROLACTAM RING AND MOLTEN CAPROLACTAM; FIBER BLENDS WITH NYLON-6; HEAT, CHEMICAL RESISTANT EDISON POLYMER INNOVATION CORPORATION (US) 1996-02-13 US disclosed
US-5480964-A CONTROLLING ORIENTATION BY SUBSTITUTION ON AROMATIC BACKBONE THE UNIVERSITY OF AKRON (US) 1996-01-02 US disclosed
US-5395918-A Heat resistance, electrical resistance and mechanical properties THE UNIVERSITY OF AKRON (US) 1995-03-07 US disclosed
WO-1994024191-A1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS THE UNIVERSITY OF AKRON (US) 1994-10-27 WO disclosed
US-5344916-A Multilayer films for optical displays using polyimide films THE UNIVERSITY OF AKRON (US) 1994-09-06 US disclosed