SCHEMBL26390454

SCHEMBL26390454

C=Cc1ccc(S(=O)(=O)NS(=O)(=O)c2cccc(S(=O)(=O)NS(=O)(=O)c3ccc(C=C)cc3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.48
▸ MCL1 Q07820 2/20 0.46
▸ PTPN2 P17706 2/20 0.40
▸ PTPN1 P18031 2/20 0.40
▸ PTPN5 P54829 2/20 0.40
▸ ALDH1A1 P00352 5/20 0.39
▸ KMT2A Q03164 4/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ CA2 P00918 4/20 0.38
▸ CA1 P00915 3/20 0.38
▸ MMP1 P03956 1/20 0.36
▸ MMP2 P08253 1/20 0.36
▸ MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10961319 0.89 TDP1 (0.52) TDP1MCL1PTPN2PTPN1PTPN5
SCHEMBL17827609 0.89 TDP1 (0.59) TDP1MCL1PTPN2PTPN1PTPN5
SCHEMBL10225934 0.80 GAA (0.52) TDP1ALDH1A1KMT2AMEN1KDM4E
SCHEMBL24036684 0.78 CA1 (0.54) ALDH1A1KMT2AMEN1KDM4ENPC1
SCHEMBL26230210 0.78 TDP1 (0.52) TDP1MCL1PTPN2PTPN1PTPN5
SCHEMBL10888017 0.78 TDP1 (0.52) TDP1MCL1PTPN2PTPN1PTPN5
SCHEMBL26406807 0.78 TDP1 (0.52) TDP1MCL1PTPN2PTPN1PTPN5
SCHEMBL26229998 0.78 TDP1 (0.57) TDP1MCL1PTPN2PTPN1PTPN5
SCHEMBL26230217 0.76 MCL1 (0.40) TDP1MCL1ALDH1A1KMT2AMEN1
SCHEMBL8733785 0.76 CA2 (0.54) TDP1CA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230347333-A1 Membranes FUJIFILM CORPORATION (JP) 2023-11-02 — — US disclosed
US-20230347333-A1 Membranes FUJIFILM CORPORATION (JP) 2023-11-02 — — US disclosed
US-20230311071-A1 Composite Membrane FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-10-05 — — US disclosed
US-20230312463-A1 Compounds, Compositions and Polymer Films FUJIFILM CORPORATION (JP) 2023-10-05 — — US disclosed
US-20230312463-A1 Compounds, Compositions and Polymer Films FUJIFILM CORPORATION (JP) 2023-10-05 — — US disclosed
US-20230311071-A1 Composite Membrane FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312463-A1 Compounds, Compositions and Polymer Films VMP1, C5, PHOSPHO1 TDP1 2762/4885MCL1 1540/4885PTPN2 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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