Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 17/20 | 0.42 |
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 3/20 | 0.40 |
| ▸ | CLK2 | P49760 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | PAK4 | O96013 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26131685 | 0.99 | GSK3B (0.42) | GSK3BGSK3APAK1CYP1A2CDK2 | |
| SCHEMBL26396381 | 0.91 | GSK3B (0.40) | GSK3BGSK3APAK1CYP1A2CDK2 | |
| SCHEMBL26396448 | 0.90 | GSK3B (0.40) | GSK3BGSK3APAK1CYP1A2CDK2 | |
| Hydrochloric Acid SCHEMBL26132356 | 0.90 | GSK3B (0.40) | GSK3BGSK3APAK1CYP1A2CDK2 | |
| SCHEMBL26396430 | 0.89 | GSK3B (0.39) | GSK3BGSK3ACYP1A2CDK2DAPK3 | |
| Hydrochloric Acid SCHEMBL26131064 | 0.89 | GSK3B (0.39) | GSK3BGSK3APAK1CYP1A2CDK2 | |
| Hydrochloric Acid SCHEMBL30581591 | 0.89 | GSK3B (0.39) | GSK3BGSK3ACYP1A2CDK2DAPK3 | |
| SCHEMBL26396408 | 0.88 | GSK3B (0.39) | GSK3BGSK3ACYP1A2CDK2DAPK3 | |
| SCHEMBL26396503 | 0.88 | GSK3B (0.41) | GSK3BGSK3ACDK2DAPK3CDK8 | |
| SCHEMBL26396394 | 0.87 | ULK1 (0.41) | GSK3BGSK3APAK1CYP1A2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |